Comment by willcipriano
Comment by willcipriano 4 days ago
The only advantage I know of for the natural way is you can retain more muscle mass potentially[0], so your relative body composition is probably better than someone who lost 75 pounds with Ozempic (eg. Ozempic Face).
[0]https://www.theatlantic.com/health/archive/2024/02/ozempics-...
[0-1] Especially if you: Try to consume about 1 gram of protein per day per gram of lean mass, lift weights, limit cardio intensity and duration (30 mins on stationary bike 3x a week worked for me)
In the first study (https://www.nejm.org/doi/pdf/10.1056/nejmoa2032183), the semaglutide group lost less LBM than the control group.
> the proportion of lean body mass relative to total body mass increased with semaglutide.
In the second study (https://link.springer.com/article/10.1007/s13679-023-00534-z), in the STEP 1 trial, the semaglutide group lost less LBM (40%) than the placebo group (56%).