Comment by djur

Comment by djur 10 months ago

Yeah, the lean mass loss effect associated with GLP-1 agonists is just the effect of rapid weight loss without lifestyle and dietary changes other than calorie restriction. There's nothing about Ozempic etc. that keeps you from eating more protein, working out more, and so on (in fact, it makes it easier to do those things in most cases). People are noticing "Ozempic face" because the people who are losing weight through calorie restriction via GLP-1 agonists previously would have just failed at dieting and kept the weight on.

willcipriano 10 months ago

> There's nothing about Ozempic etc. that keeps you from eating more protein, working out more, and so on

Except that the population that takes it never develops those skills.

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consteval 10 months ago

Not necessarily true - it's a lot easier to workout when you're actively losing weight. Obese people aren't stupid, they've tried working out before. Turns out it's hard, it hurts, and the benefit you get from working out in relation to weight is slim to none. If they're on the right track already and their mind a little clearer, I'm sure it makes it more likely for them to work out.
It's also easier to workout if you don't drink and smoke, which Ozempic also helps with.

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- djur 10 months ago
  
  Thanks. Yes, this is exactly true, I can testify from personal experience. And GLP-1 agonists also often seem to make it easier for people to make good dietary decisions. When you're not driven as much by cravings, you will find it easier to resist hyperpalatable foods.
  
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