Why go this route? Why Python is more powerful than JS is mostly because of third party plugins like pandas which are excplicitly not supported (C bindings, is this possible to fix?)...
At that point it might be just easier to convince the model to write JS directly
I would love for the component model tooling to reach that level of maturity.
Since the runtime uses standard WASI and not Emscripten, we don't have that seamless dynamic linking yet. It will be interesting to see how the WASI path eventually converges with what Pyodide can do today regarding C-extensions.
You can run libraries like Pandas in WebAssembly in Pyodide - in fact Pandas works already. Here's a demo I built with it a while ago: https://tools.simonwillison.net/pyodide-bar-chart
It's not too hard to compile a C extension for Python to a WebAssembly and bundle that in a .so file in a wheel. I did an experiment with that the other day: https://github.com/simonw/tiny-haversine?tab=readme-ov-file#...