Comment by JeremyNT

Yeah this is a really wild experiment.

Their hypothesis for the mechanism is "gut bacteria" but these people in the study all had a trifecta of "high" body weight (overweight? obese? not specified in this article), high blood pressure, and hyperlipidemia.

So we've got some unhealthy people, we cut their calories to less than half, we jack their fiber way up (most likely - we don't know their baseline diet but with those biomarkers we can make some educated guesses), we restrict the timing of when they eat and remove all junk food.

So is this oatmeal specifically? Fiber? Calorie deficit? Meal timing effects? Removal of processed food for two days?

The idea that you can "shock" your body to better biomarkers like this and have it last over a month is extremely cool, but I wonder how they can be certain that this is some oatmeal thing versus a general "eat way less and limit yourself to a food that is high in fiber" thing.

The low protein here is a problem when in a calorie deficit, for example, because if you don't have enough protein you're likely to lose weight as muscle mass rather than fat. If you could do the same technique with legumes your protein would be way better.