Comment by toomuchtodo

And I can provide examples of Metformin being very safe with the exception of a few edge cases, while providing exceptional benefit across a wide cross section of the population. Could something exceptional crop up? Potentially. But so far, the data is very compelling GLP-1RAs have a reasonable safety profile for the enormous benefit provided.

https://intermountainhealthcare.org/blogs/article/your-frien...

> Are GLP-1s safe? What are the side effects? > GLP-1s have been extensively studied and are considered safe when prescribed and monitored by a healthcare provider.

With all of this said, I'm open to having a mutually agreed upon subject matter expert provide the equivalent of an opinion letter on the safety of GLP-1RAs at my (reasonable and customary) cost. Feel free to propose one.