Comment by simoncion
Not all anticheat fails to work in Wine/Proton.
The super invasive kernel-mode variants (that is, the sort that's in Valorant) flat out fail, and surely always will. It's my (perhaps mistaken) understanding that with some others (like Easy Anti Cheat), it's a choice made by the game dev as to whether running in Wine/Proton will be permitted or not.
That's not exclusive to kernel-mode anti-cheats. Even VAC, which is not kernel-mode, doesn't work in Proton: https://github.com/ValveSoftware/Proton/issues/3225