Comment by cam_l
It probably depends a lot on your parents.
I went with Popos. It is simpler than KDE for someone with dexterity and mild cognitive issues. Plus it fixes a lot of the annoying ubuntu / gnome decisions like snaps and hiding the taskbar etc.
There were a few initial teething questions in the first week, but 6 months in now and no other issues (apart from forgetting her password). Highly recommend.
PopOS is great, but I wouldn't recommend it right now while the new DE is in beta.