Comment by mickeyp
These are my PRAGMAs and not your PRAGMAs. Be very careful about blindly copying something that may or may not match your needs.
PRAGMA foreign_keys=ON
PRAGMA recursive_triggers=ON
PRAGMA journal_mode=WAL
PRAGMA busy_timeout=30000
PRAGMA synchronous=NORMAL
PRAGMA cache_size=10000
PRAGMA temp_store=MEMORY
PRAGMA wal_autocheckpoint=1000
PRAGMA optimize <- run on tx start
Note that I do not use auto_vacuum for DELETEs are uncommon in my workflows and I am fine with the trade-off and if I do need it I can always PRAGMA it.defer_foreign_keys is useful if you understand the pros and cons of enabling it.
Using strict tables is also a good thing to do, if you value your sanity.