Comment by _DeadFred_

By this point, 'professional astronauts' is just another term for 'space truckers'. The film makers put in a lot of effort to point that out. Switch that in your head and it makes more sense. They have done so many routine missions, and it's all so routine, that they aren't prepared for non-routine. The whole structure of missions leaves the non-routine handling to synthetics. These are like key components of this franchise what the story it's trying to tell.

We reached the stars, but became alienated from both exploration and ethics. We lost the wonder and lost control of our fate. Life has become routine labor, corporate control, and synthetic oversight that isn't looking out for our best wishes even though we assume it is.