No keypad, no pageup/pagedown/home/end/delete (I use all of them very frequently), arrow keys are misplaced and tiny (also use them a lot), no F1-F12 keys, no screenshot button, funky command key instead of using control key like any sane OS, and the command key is where the option key belongs, blah blah.
Yes, inane.
Why would you want to use a Control key that's hard to reach when the Command key is right under your thumb?
I'm only just now using a Mac again after not using them since elementary school. Tucking my thumbs under the rest of my hand to press the command key is a motion I'm really not used to, while as before I was really used to using my pinky to press/hold the control key often.
I do have to say though, its nice not having to worry about situations where I need to remember some odd shortcut for something that actually supports control characters like text consoles. I never need to worry about "does ctrl+c actually copy here, or does it kill things?" They're just different button presses. I get the logic these days of having those things be different keypresses than control key logic.
A lot of keyboard shortcuts I use daily now feel quite alien because of tucking my thumb under to reach the command key. And boy is it sometimes annoying having so many shortcuts using number keys in them. And the common jump between words or jump to the end or start of a line seem to be backwards in my mind (command+arrow versus option+arrow), I tend to get mixed up on those a bit right now.
The OS supports all of those keys still. Yeah you don't get them on a laptop keyboard but I rarely use the laptop keyboard as is, it's docked 80+% of the time for me at my desk so I have a nice full size keyboard I use.
Never missed a dedicated screenshot button though, I always just Cmd+Shift+4