Comment by jdiez17
There are many Raspberry Pis on the International Space Station (AstroPis). They're subject to a similar amount of space radiation as CubeSats in LEO, and they work just fine. There's also an increasing trend of building CubeSat On-Board Computers (OBCs) as some form of Linux System-on-Module (these would traditionally be microcontrollers). I think Raspberry Pis (especially the Compute Modules) are quite suitable for Payload Data Handling (PDH) systems, although I've personally not had a chance to launch a RPi chip yet.
But even in LEO, there must be quite a few SEUs and resets?