Comment by jimmaswell a day ago
Vaping nicotine doesn't seem that bad to me. AFAICT the dangers outside simple addictiveness are moderate lung irritation and cardiovascular effects, but no strong evidence of cancer caused by vaping alone - far better than cigarettes, and still better than an equivalent drinking problem.
Vaping causes inflammation, nicotine suppresses the immune system (which is probably pretty bad news for fighting any other diseases), and nicotine cessation has been linked with an increase in development of autoimmune disorders in the 12-24 month period after quitting.
I had elevated white blood cells counts and I developed an autoimmune condition a few months after quitting vaping. I had good health record leading up to it and no family history of any autoimmune disorders. White blood cells eventually normalized but autoimmune is forever, although it's under control and I'm lucky that it was caught early.
In the final ~4 years of vaping I didn't use any flavorings either, just 70/30 mix of VG/PG and nicotine.
It's not terrible as far as vices go, much less harmful than the alternatives, but it's definitely not as harmless as I thought going in. I wish I hadn't started and went for the ADHD assessment right away instead of subconsciously self-medicating with nicotine.
> linked with an increase in development of autoimmune disorders in the 12-24 month period after quitting
No shit, I had no idea.
That explains a lot. I quit smoking (well, the first time I tried to quit) when I was 19 (2 years smoking). 3 months later I was in the hospital with sclerosing mesenteritis, a rare disorder for an older person but baffling and way out of left-field for a 19 year old with no prior history autoimmune issues. We only got a diagnosis after full exploratory surgery that earned me a six inch incision scar on my stomach.
Don't start smoking, kids.
I don't think adequate studies have taken a look into the long term effects of all the solvents and oils they use aside from the nicotine. Intuitively, this just seems like a terrible idea putting non-water-soluble vapors into your lungs but I am definitely not a doctor.
It's not exactly a wild list. You can make your own mint vape liquid at home by combining 1 part vegetable glycerin with 1 part glycol, dissolving nicotine salt to the desired concentration (most dangerous part due to nicotine's toxicity, suggest getting it pre-dissolved in either one or both of the above), then dissolving menthol in to taste.
Don't get me wrong: it's not good for you, but it's a lot less bad for you than cigarettes, and it's not some great mystery as to what's in it.
This is why to me it’s so damn disappointing to me that vaping is targeted so forcefully by the various scolds in the “regulate everything” camp when smoking isn’t yet eradicated. Things like banning flavor and stuff. They want it to be as unpleasant as tobacco, which reduces the likelihood of people switching from tobacco to vaping, killing many of those smokers as a way to “save” teens from taking up an overall not-very-dangerous habit.
> They want it to be as unpleasant as tobacco
I vaped for around 8 years, about 4 years with typical flavorings and the last 4 years unflavored. IME unflavored vaping really isn't that bad, I accidentally switched to it because I ran out of flavoring one time and after a few days I didn't really miss them anymore so I just stopped using them.
I would compare it to people who drink soda all day, they can't fathom how people can drink "boring" plain water all day and they have a really hard time switching, but people who are used to drinking water find it as refreshing and satisfying as anything.
I think these flavorings cause more harm by luring young people to start vaping than they help smokers by luring them away from cigarettes. In an ideal world adults would be allowed to vape whatever they want, and teens wouldn't be able to get their hands on vapes in any capacity, but clearly that's not working so I think that flavor bans are a decent compromise.
I don't buy the argument that flavor bans will make teens go back to smoking. Cigarettes taste awful, they make you smell terrible, they irritate your lungs far more, they're far more expensive. If I was a teen I would still pick up unflavored vaping over cigarette smoking any time, but I'd be less likely to get into vaping without the flavorings.
A counterpoint:
> A third of UK teenagers who vape will go on to start smoking tobacco, research shows, meaning they are as likely to smoke as their peers were in the 1970s.
> The findings suggest that e-cigarettes are increasingly acting as a “gateway” to nicotine cigarettes for children, undermining falling rates of teen smoking over the past 50 years.
https://www.theguardian.com/society/2025/jul/29/third-of-uk-...
As an adult with a vaping habit, I can see how that happens. If you're a kid, and thus have unstable access to nicotine vapes (because they're illegal for you to buy), you'll be highly motivated to get your nicotine fix from something if your source of vape liquid dries up. Since cigarettes are more common, the result is a kid being likely to smoke sometimes.
Same thing happens to me (albeit far, far less frequently) when I'm out at the bars with my friends until 2am when I discover I'm out of juice. Since vape shops tend to keep normal retail hours, I'm limited on getting my fix from whatever the 7/11 is selling. If that's Marlboro reds, I'm probably going to smoke a cigarette or two.
Key difference between it being a "gateway drug" and not is the fact that I'll end up throwing away that pack the next day when I can refill my vape. Because smoking sucks in comparison. Not only on health grounds (not a huge concern for most nicotine addicts), but on basic grounds like "making you smell like shit", "hurting your throat", "tasting bad", and "not having the oppurtunity to be used nearly as frequently".
Maybe I'm just an old geeser but when I went back to grad school I was absolutely shocked at how many people vaped, and it seemed to have been because they started smoking flavored vapes. People would go to a party, either in high school or college, and the party would be permeated by some sweet smell. Curious kids/people would investigate, try vaping, and eventually get their own, becoming addicted.
As far as I can tell, banning flavored vapes has had a significant impact on reducing vaping/smoking new users, which is the ultimate goal. People who are currently addicted should primarily be motivated to quit, not find better tasting alternatives
Counter-point: For someone who's used to smoking or vaping, the craving to "take a puff" can be a very strong, maybe stronger than the chemical dependence on nicotine itself.
I noticed that in myself when I was trying to quit, vaping nicotine-free liquids helped my cravings more than nicotine itself. It didn't help the physical withdrawal symptoms but it mysteriously stopped the cravings for a while.
Amazingly, nicotine is one of the few things in tobacco smoke that isn't carcinogenic.