Comment by perrygeo

Unfortunately the homebrew cask is still Intel-only so it requires Rosetta, whereas the conda/mamba version has an osx-arm64 build. There are other workarounds discussed here: https://github.com/qgis/QGIS/issues/46299 and here https://geo.malagis.com/native-qgis-on-apple-silicon-solutio...