Comment by kixelated
Chrome and Firefox support WebTransport. Safari has announced intent to support it and they already use QUIC under the hood for HTTP/3.
Cloud services are pretty TCP/HTTP centric which can be annoying. Any provider that gives you UDP support can be used with QUIC, but you're in charge of certificates and load balancing.
QUIC is client->server so NATs are not a problem; 1 RTT to establish a connection. Iroh is an attempt at P2P QUIC using similar techniques to WebRTC but I don't think browser support will be a thing.
Last I checked, Iroh is gonna use WebRTC datachannels to run QUIC over SCTP