Comment by gavinray
TiHKal and PiHKaL are fulls of synths that require equipment and re-agents far beyond what a hobbyist would be able to source.
There are various "one-pot" techniques for certain compounds if one is sufficiently clever.
For example, a certain cathinone can be produced by combining ephedrine/pseudoephedrine with a household product that reduces secondary alcohols to ketones and letting it sit.