Comment by dagw

Can it do GUIs well?

I don't know if I would say 'well'. For simple GUIs it's OK but, for non-trivial GUIs I would use the approach to write the GUI frontend code in C# and have it call the F# 'backend'. If for no other reason than that the support and documentation for doing GUIs in C# is much better.

How about mobile?

Never tried, but I'm guessing more or less the same story as above. I would probably start by looking into .Net MAUI for that.

And how does it compare to e.g. Scala?

The biggest difference is that Scala is a much bigger and more of a multi-paradigm language. F# feels smaller and more focused and on its ML roots and functional programming. Not saying that Scala is less 'functional' than F#, but Scala supports you writing your code in a much more OOP way if you want. Yes you can (and sometimes have to) do OOP in F#, but it doesn't feel natural.