Comment by SkyPuncher 15 hours ago
I don't think it was ever really a debate.
"Reduce calories" is about as useful as "exercise more", "sit less", "drink less", etc, etc. All are obviously good, but for various reasons it can be hard for people to achieve them.
GLP-1's basically take the "how" out of the equation. Take this drug, eat less without fighting your own desires.
Yes, "eat less" is the answer, but this is harder to do yeah if your metabolism is slow or always being hungry. this drugs makes it easier to eat less and hence lose weight .
there are plenty of people who claim that no amount of calorie reduction results in weight loss. Often it's people who are claiming to eat starvation amounts of food while gaining weight. Of course researchers have known it was delusional, but the belief persisted in pop culture. Ozempic is putting that to rest.
this is a case where more personal / colloquial / folk evidence was needed to convince people.
I doubt that the people who believe that obese people somehow violate the first law of thermodynamics will be convinced to change their mind now, just because Ozempic became a thing. They will probably just misunderstand how the drug works.
All of them are essential as an objective to implement or improve the how.