Comment by arcticbull

Comment by arcticbull 2 months ago

16 replies

Ah, gotcha.

For what it's worth CICO sucks because (1) nobody can stick to it, ever (2) humans are awful at estimating their calories in, studies show only 1/5 of people can properly estimate the calorie content of their food [1] and (3) your metabolism slows down in response to, specifically, caloric restriction diets and your hunger rises which makes it difficult to estimate your calories out without indirect calorimetry.

Yes, CICO works in a lab, and for some weird people. It's a matter of thermodynamics. However you are a far more complex system than a coal powered furnace. And yes certain types of food will be more or less satiating and may influence the amount of total calories you consume. It's really really hard to overeat if you just eat lean protein, for instance.

CICO is, in practice, a tool that is roughly impossible for most people to leverage to lose a meaningful amount of weight and keep it off.

Which brings us back to the difference between maintaining a persistent caloric deficit -- and instructing people to do so.

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC3719184/

JoshTriplett 2 months ago

> and (3) your metabolism slows down in response to, specifically, caloric restriction diets and your hunger rises which makes it difficult to estimate your calories out without indirect calorimetry.

This is the critical one that leads people to correctly argue CICO is largely useless for attempting to lose weight: the "CO" part of that is highly variable and is not merely a matter of being active. The body has all sorts of mechanisms that it can adjust to achieve the amount of storage vs burning that it wants to do, regardless of the amount of food consumed or the activity level.

  • phil21 2 months ago

    The metabolism slowing down thing is greatly over exaggerated. Everything I’ve read that is evidence based puts it at a nominal difference.

    Put simply: starvation mode is a myth for everything but outliers that are uninteresting to discuss.

  • paulpauper 2 months ago

    yes, this. the body decides to become super-duper efficient like a Prius. this is shown by studies in which acts like walking burn less energy . There is a lower threshold in which weight loss must occur, but this can be way lower than predicted by calculators or naive CICO estimates.

nemomarx 2 months ago

Why are people trying to estimate calories blindly? You have to look them up in some sort of system and log it in a food journal for the tracking to be any good at all.

  • [removed] 2 months ago
    [deleted]
bena 2 months ago

It works for everyone.

Full stop.

Even if your metabolism slows down in response to caloric restriction, it does not move the needle to any appreciable degree.

Because it takes energy to do. It just does, you cannot fool physics.

However, measuring calories is incredibly difficult. Both in and out. Also, if you put 5000 calories worth of food inside of you, but then immediately vomit out 4500 of those calories, you've only really consumed 500 calories. You can overwhelm the system.

If you can restrict yourself to consuming at a caloric deficit, you will lose weight.

That's difficult however. Because if you pick a target calorie amount, you will see less progress as you lose weight. Because of math. 1500 is half of 3000, but only a quarter of 2000. People get fixated on 2000, as if we operate based on 2000 calories a day. But if you were previously consuming 3000 calories a day, your weight requires 3000 calories a day. So when you drop to 1500, you are going to lose about a pound every two days for a while. When you get to about 2500 maintenance calories/day, you're going to slow down to a about pound every three days. This is not your metabolism "adjusting". You weigh less, it takes fewer calories to maintain that weight.

And you will be hungry. It will suck. And you have to be meticulous in your record keeping. There are no "free" calories.

And we're not even getting into the mental component of all of this. What's been termed as "food noise". And it's one of the things that people on Ozempic and the like notice the most, they stop thinking about food. And food addiction is one of the absolute worst addictions to have. Hands down. With just about every other addiction, abstinence is an option. Alcohol, gambling, heroin, cocaine, meth, etc, none of that is necessary to live. We need food. We need to eat. You cannot avoid food. You have to actually develop discipline. Teetotalers do not have discipline. They avoid the issue altogether.

So CICO works, but it's incredibly difficult to do for lots of reasons that are not related to the biology or physics of it.

  • paulpauper 2 months ago

    Yup, and where this stall vs. weight occurs is mediated by genes to a large extent. Someone who stalls out at 1.8-2.2 kcal/day while still being obese will need extra help, when cutting more calories is too unpleasant (many such cases). This drug makes that easier. And there is no evidence to suggest it gets easier with time or the body at some point stops trying to put the weight back on. Dieting is 24-7 war on food.

    • kjkjadksj 2 months ago

      It is easier if you couple this with exercise. Many people successfully lose weight with exercise and managed diet. You have to want to do it to a certain extent. I think the solution for people who lack willpower for this isn’t ozempic, its therapy for the underlying depression that probably bleeds into all other aspects of life.

      • paulpauper 2 months ago

        medication makes things easier. I think it's better to use technology to make life easier than to be resistant to it and make life unnecessarily hard.

  • 8note 2 months ago

    CICO also wants you to collect your poo, so you can check the CO of it in a bomb calorimeter

s1artibartfast 2 months ago

FYI, GLP1 drugs are CICO - they work because they reduce calories in.

It CICO is physics, not a complete instruction set for life. I dont understand why it makes people so angry.

  • paulpauper 2 months ago

    "you're doing CICO wrong. you can only lose weight in the way I approve of"

kjkjadksj 2 months ago

People not being serious about diet and exercise doesn’t mean it doesn’t work. Look at reality tv where there is calorie restriction, like Alone or “Survivor” and everyone loses weight. On the former in particular people have lost like 40 pounds in as many days before and have lost so much weight so fast that medical teams have pulled them from the show.

This is like saying most people barely use 5lb dumbbells when told to work out, so working out must not work. Like, of course major lifestyle changes take willpower!

paulpauper 2 months ago

CICO works if you have the patience and discipline to make it work, which few do. At some point it becomes too unpleasant to keep reducing calories or to measure and track everything. Life gets in the way.