Comment by gizmo686

Casting integers to pointers in C is implementation defined, not UB. In practice compilers define these casts as the natural thing for the architecture you are compiling to. Since mainstream CPUs don't do anything fancy with pointer tagging, that means the implementation defined behave does exactly what you expect it to do (unless you forget that you have paging enabled and cannot simply point to a hardware memory address).

If you want to control register layout, then C is not going to help you, but that is not typically what is meant by "memory layout".

And if you want to control cache usage ... Some architectures do expose some black magic which you would need to go to assembly to access. But for the most part controlling cache involves understanding how the cache works, then controlling the memory layout and accesses to work well with the cache.