I'm only aware of the differences with manual timings but if you're not running the bottom of the (1 DIMM per channel) barell frequencies like 5200-5600 differences from going higher should be minimal.
Not that many things actually scale with bandwidth so the higher frequencies are mostly helping because ther'll be shorter delays between operations where the registers for the timings bottom out at a higher number.
AMD also needs to change the sync of memory controller clock to memory clock to 1:2 instead of 1:1 above ~6000-6400 so as some anecdata 7800 performed roughly the same as 6000
I'm only aware of the differences with manual timings but if you're not running the bottom of the (1 DIMM per channel) barell frequencies like 5200-5600 differences from going higher should be minimal. Not that many things actually scale with bandwidth so the higher frequencies are mostly helping because ther'll be shorter delays between operations where the registers for the timings bottom out at a higher number.
AMD also needs to change the sync of memory controller clock to memory clock to 1:2 instead of 1:1 above ~6000-6400 so as some anecdata 7800 performed roughly the same as 6000