Comment by viraptor

Comment by viraptor 4 days ago

14 replies

Yes, a few types are basically a numbers game. We're continuously successfully not getting them every day. But the longer we live and not die of other things, the higher chance there is of losing that game. And we're actually getting quite good and not dying of other things.

Then again, cancer treatments and vaccines are progressing recently, so that's good news.

guerrilla 4 days ago

This sounds good, but it can't be right. There are animals that live centuries. Greenland sharks may live up to 500 years, for example. There are trees that live millenia.

  • thfuran 4 days ago

    But they aren't human. We don't survive being dessicated and heavily irradiated like a tardigrade or regrow severed limbs like starfish, and we aren't as good at avoiding cancer as some other animals.

    • cogman10 4 days ago

      And some animals are worse. Dogs, for example, are most likely to die from cancer. They also get cataracts decades earlier than humans do.

    • guerrilla 4 days ago

      You're supporting my point. The reason we suffer from this is not solely probabilistic. There are many other factors.

  • kragen 4 days ago

    being warmblooded is a huge disadvantage for longevity

    • AlphaCharlie 4 days ago

      Can you expand on that subject? What are the traits of warm blooded species that lead to higher cancer rates?

      • kragen 4 days ago

        not just higher cancer rates, but higher rates of all kinds of aging-related deaths

        the advantage of being warm-blooded is that your metabolism is more precise and much faster, but, as james dean quoted willard motley saying, 'live fast, die young'

        most of the causes of aging are unwanted chemical reactions; https://www.cell.com/action/showPdf?pii=S0092-8674%2813%2900... is a highly-cited paper reviewing what we knew about the causes of aging 11 years ago. chemical reactions of all kinds follow the https://en.wikipedia.org/wiki/Arrhenius_equation which makes them happen about 2–3 times faster per 10° temperature rise

        (being old is a more important risk factor for cancer than anything else i can think of, even smoking and radioactive fallout)

        small sharks around greenland, to take an extreme example, are at essentially the temperature of the seawater, about -1.8°. larger sharks could conceivably raise their internal body temperature, but greenland sharks swim very slowly to avoid this even when they are large. so their metabolism is about 16× slower than yours is—both healing and aging processes happen slower. their gestational period is about 8–18 years

      • pfdietz 4 days ago

        Probably constant generation of reactive oxidizing chemicals from the higher metabolism needed to maintain body temperature.

  • [removed] 4 days ago
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freedomben 4 days ago

I don't think prolonging the life in a biological body is going to be the winning route. We will have to Star Trek it up and transfer our consciousness to computers. That, or replace parts, maybe even the entirety of our bodies with a machine that can be maintained and repaired rather than age.